Published: 26 Mar 2024

Reference Ranges and Optimal Health Ranges

Reference Ranges

* Provide a basis for interpreting patient test results.
* Represent the normal range of values observed in the population (usually with a 95% prediction interval).
* Serve as a benchmark for identifying abnormal results.
* May also be referred to as standard ranges.

Optimal (Health) Ranges

* Thresholds associated with optimal health or minimal risk of complications.
* May differ from reference ranges, especially for vitamins and blood lipids.
* Reflect the desired concentrations or levels for promoting health.

Standard Definition of Reference Ranges

* Typically derived from the most prevalent values in a healthy population reference group.

Distinction between Usual and Optimal Levels

* Usual reference ranges indicate common values in the population, while optimal ranges represent ideal levels for health.
* For most substances, optimal levels are found near the central tendency of the population distribution.

Reference Intervals

* Describe the range of values observed in healthy individuals for a specific measurement or test.

Lab Test Results

* Must be evaluated against the reference ranges provided by the performing laboratory.
* Variations can occur due to differences in testing equipment and techniques.

Understanding Lab Results

* Few reference ranges are provided online due to variability in laboratory testing.
* Health professionals are better equipped to interpret test results and provide guidance on their significance.